ea0099p312 | Pituitary and Neuroendocrinology | ECE2024
Fenger Dreyer Anja
, Kold Jensen Tina
, Have Beck Iben
, Glintborg Dorte
, Bilenberg Niels
, Andersen Marianne
Background: Maternal cortisol levels increase during pregnancy and prenatal cortisol exposure have been linked to cognitive function in childhood. Higher activity of the enzyme 11β-hydroxysteroid-dehydrogenase type 2 (11β-HSD2) downregulates the amount of maternal cortisol crossing the placenta by inactivation of cortisol to cortisone. In childhood, boys perform significantly poorer in tests of intelligence than girls.Aim: To investigate associ...